Recombinant adeno-associated viruses (rAAVs) have emerged as one of the most promising gene therapy vectors that have been successfully used in pre-clinical models of heart disease.However, this has not translated well to humans due to species differences in rAAV transduction efficiency.As a result, the search for human cardiotropic capsids is a ma
The new anthropomorphic stone stele with a single Sarmatian tamga, originating from the Solonets River gorge and located near Rosieticii Vechi and Rogojeni in Northern Moldavia, does not belong to the typical Sarmatian stone steles.A Sarmatian tamga is carved on the face of the monument.This symbol has a number of analogies in terms of the carving
In the 2000s, the idea of a so-called middle-segment arose in North-West Europe to address the criticism on ATLAS CEDAR intensive broiler production systems.Middle-segment systems being indoor housing of slower-growing broiler strains at a stocking density ≤38 kg/m2.Previous literature showed that Dutch middle-segment systems entail a relativ
Abstract Background A microsponge delivery system (MDS) is an innovative and unique way of delivering drugs in a structured manner.Using microsponge drug delivery, regulated drug delivery may now be achieved quickly and easily.Main body MDS comprises porous microspheres ranging in size from 5 to 300 microns, with a large porous structure and a very